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Studies indicate that in the absence of appropriate medical intervention, approximately 20% of patients with diabetic wounds will require lower limb amputation, with a subsequent one-year mortality rate of 13% post-diagnosis 19,20

The early data suggests it could be the most effective medication yet for both type 2 diabetes and obesity, with the added benefit of directly improving liver health

Nature (2015) 528(7581):2626.10.1038/nature15766 191 WuHEsteveETremaroliVKhanMTCaesarRManneras-HolmLet alMetformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

Some evidence suggests that taking it before the largest meal of the day may optimise the postprandial hormone response