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Since Wegovy and Ozempic were approved for different indications, we could not directly assess the dosage effect of semaglutide on CUD in the same study population

Compared to the other trials investigating GLP-1RAs, the ELIXA trial included T2D patients with recent acute coronary syndrome (ACS), suggesting that perhaps their CV risk was too severe to demonstrate a simple decline in CV events via short-term pharmacological intervention