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Nat Cell Biol 25:14051405 Alborzinia H, Ignashkova TI, Dejure FR et al (2018) Golgi stress mediates redox imbalance and ferroptosis in human cells

It ultimately increases the production of oxidative protein folding-mediated reactive oxygen species (ROS) (251)

Cocci A, Cito G, Urz D, Minervini A, di Maida F, Sessa F, et al

However, given the presence of GLP-1R in the ARC and the direct contact of the ARC with the circulation, it is plausible that GLP1-RAs could have a direct effect on the hypothalamus, on the proviso that GLP-1RA levels exceed physiological levels of GLP-1