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In the following discussion, forms found in food or the body are referred to as "folates," while the form found in supplements or fortified food is referred to as "folic acid." Function One-carbon metabolism The only function of folate coenzymes in the body appears to be in mediating the transfer of one-carbon units (2)

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Aetiology Current evidence suggests that around 85% of SJS/TEN cases are caused by medicine that is initiated in the preceding eight weeks of disease presentation, with the remaining cases being of unknown aetiology or, more uncommonly, Mycoplasma pneumoniae or herpes simplex virus (HSV) infections [3], [5], [6]

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