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By intervening in this process, FOXO4-DRI specifically targets these senescent cells, triggering their death and thereby mitigating their contribution to aging and age-related diseases

Mice were group-housed on 12 h:12 h light cycle with ambient temperature of 2026 C and relative humidity in range of 4070%

Chloroplast membrane integrity and photosynthetic efficiency Chloroplasts are a primary location for the generation of ROS in plant cells and they have been reported to be the most sensitive organelles to abiotic stress 46,47,48

This could explain why E3 exhibits higher-than-expected biological activity compared to E2