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EP patent 146,265 Gushima H, Miya T, Murata K, Kimura A (1983) Construction of glutathione-producing strains of Escherichia coli B by recombinant DNA techniques

Contributing Factors The causes of uneven skin tone may include: Pollution Dehydration Nutrient deficiencies Poor Skincare habits Underarm or Intimate Area Darkening Hyperpigmentation on the underarms or intimate areas is quite common, yet the least talked about in Pakistan

Some reports ( Reference Betz, Ren and Ennis 53 Reference Seekamp, Hultquist and Till 56 ) have indicated that riboflavin can alleviate oxidative injuries in these situations, probably through its ability to scavenge free radicals

This approach reduces formulation complexity and cost, while also contributing to the development of products with improved purity and health profiles