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The key challenge lies in the fact that both medications require particular conditions for optimal absorptionlevothyroxine needs an empty stomach with minimal interference, whilst Rybelsus requires specific timing and fasting conditions to ensure adequate bioavailability through its unique absorption mechanism

43 With regard to HF with preserved ejection fraction (HFpEF), initial data suggest a benefit of tirzepatide and semaglutide in patients with obesity

Obesity Medicine Association

JCYJ20170412110026229 and JCYJ20200812122708001), and the Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions (Grant Nos