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She was initially concerned that the side effects were affecting her child's growth

The Cochrane Library, Web of Science, PubMed, Embase, and the ClinicalTrials.gov website were all searched until May 25, 2025

Taken together, lean mass reduction during GLP-1 receptor agonist-associated weight loss is best understood as a predictable consequence of sustained negative energy balance, reduced mechanical loading, and broader metabolic adaptation rather than as a direct catabolic effect of GLP-1 receptor signaling

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