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Both oral and injectable semaglutide carry similar risks, including: Acute pancreatitis Diabetic retinopathy complications (diabetes-related vision changes) Hypoglycemia (low blood sugar), especially when used with insulin Kidney or gallbladder issues Severe gastrointestinal reactions Allergic reactions Pulmonary aspiration during general anesthesia or deep sedation Additionally, Wegovy carries warnings for increased heart rate and suicidal behavior or ideation