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For a drug to be approved for the pregnant population, it must go through rigorous testing with that population, and that has not yet happened for semaglutide or other GLP-1 (glucagon-like peptide 1) agonists, says Carrie Burns , MD, a board-certified endocrinologist and director of diabetes in pregnancy at Penn Medicine in Philadelphia

It can feel stickier, more persistent, or oddly unrelated to how much water someone drinks

Bazinet RP, Weis MT, Rapoport SI, Rosenberger TA

Mikki may recommend combining it with hormone replacement therapy for comprehensive hormonal optimization, NAD+ therapy for cellular energy and longevity, MOTS-C for metabolic support, aesthetic treatments to complement internal wellness with external rejuvenation, and medical weight management if body composition is a primary goal