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As we explained in the CY 2026 PFS proposed rule (90 FR 32656), we believe this proposed approach strikes a balance between (1) policies that support growth of the Shared Savings Program by allowing for participation under a one-sided model for up to the entirety of an eligible ACO's first agreement period, and (2) policies encouraging participation in performance-based risk which we believe have the potential for increased effectiveness towards meeting the program's goals

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Acetyl L-Carnitine's overall importance is underscored by its role in the brain where it can bypass the blood-brain barrier to deliver its benefits directly to the brain