thioredoxin glutathione Involvement of glutaredoxin-1 and thioredoxin-1 in β-amyloid toxicity and Alzheimer's disease A comparison of the reaction

This binding cooperativity results from the molecule's ability to also mimic the homodimeric structure of Smac, which is functionally important for reactivating caspases

102 Some data indicates that among the neuroprotective effects of nicotine is the ability to reduce alpha-synuclein aggregation, which may suppress the formation of Lewy bodies

1 Introduction Cardiovascular diseases (CVDs) remain the leading cause of mortality and disability worldwide, imposing an enormous health and economic burden

These effects may be ascribed to their antioxidant, anti-inflammatory, and neuroprotective capabilities as evidenced by various studies 131,132