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Koikov L, Starner RJ, Swope VB, Upadhyay P, Hashimoto Y, Freeman KT, Knittel JJ, Haskell-Luevano C, Abdel-Malek ZA

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The PERK-ATF4-CHOP pathway is a central signaling cascade activated in response to ER stress, serving as the cells primary reaction to dysfunction and playing a crucial role in cellular survival