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Cost alone is not a clinical reason for an off label partial dose

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The key terminal effector factors in these G-protein receptor signaling cascades are focal adhesion kinase (FAK), nuclear factor beta (NF-B), nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, eNOS, STAT3, and B-cell lymphoma-extra-large (Bcl-xl) (780)