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Analysts at the time were bullish about these findings, with BMO Capital Markets noting that orforglipron achieved injectable like efficacy. Study participants also lost 7.9% body weight after orforglipron treatment, as compared with 1.6% in placebo

Instances of delayed gastric emptying can occur even after patients have been taking GLP-1 RAs for more than three years

Key finding from recent research highlights the risks associated with GLP-1 therapy: Despite a less than 1% overall risk, the findings suggest a consistent elevated risk in comparison to those not on these medications