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Homocysteine can either be remethylated back to methionine or diverted into the transsulfuration pathway to produce cysteine (the precursor to glutathione)

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Here is why: Glutathione inhibits tyrosinase the enzyme that triggers melanin production in response to UV radiation

A notable example is the exclusion of several SGLT-2 inhibitors (e.g., dapagliflozin, canagliflozin, empagliflozin) due to missing pathway annotations, which restricts the comprehensiveness of our framework despite their widespread use and emerging evidence for neuroprotective effects in AD