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Importantly, tricyclic antidepressants, especially amitriptyline and nortriptyline, worsen the metabolic profile, increasing insulin resistance, contributing to weight gain and causing hyperglycemia, thereby increasing the risk of diabetes with prolonged use [77]

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2006) the mean latencies for the scopolamine group (mean latency to find the pedestal = 84.8 s) and the scopolamine + Hinge Dihexa group (mean latency = 93.6 s) indicated little improvement in learning compared to the vehicle control group (mean latency = 43.0 s), the Hinge group (mean latency = 46, 1 s) and the scopolamine ~ Dihexa group (mean latency 62.3 s)