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Specifically, we proposed to amend 425.605(h)(1) by adding new paragraph (v) that specifies: For agreement periods beginning on or after January 1, 2027, the ACO has at least 5,000 assigned beneficiaries in each of the ACO's benchmark years. The proposed timing of applicability for this policy would be consistent with the timing of applicability for our proposed approach to allow participation by ACOs with 5,000 assigned beneficiaries in BY3, and fewer than 5,000 assigned beneficiaries in BY1, BY2, or both

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An RNA-seq analysis of the renal outer medulla identified nine pathways that were altered between SS rats on a diet containing 0.4% salt and after seven days on the same diet containing 4% salt 24