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When you take semaglutide, it: Slows down food movement through your stomach, so you stay full longer Sends signals to your brain that you're full faster Stimulates insulin release after a meal to prevent blood sugar spikes Reduces the amount of the hormone glucagon so that the liver releases less stored glucose into the blood, which helps maintain steady blood sugar levels Types of semaglutide Semaglutide comes in two main forms: Injectable semaglutide is administered under the skin once weekly