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Soluble UA can reduce the number of monocytes positive for pro-inflammatory cytokines IL-6 and TNF-alpha 35

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Practical safety measures include routine lab tests and cardiovascular assessments under qualified supervision

For cardiovascular models, T4 was delivered via retroinfusion into the anterior interventricular vein in a hypoxia-reoxygenation pig model, or through intracardiac or intraperitoneal injection in murine permanent ligation models