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A large trial reported in 1994 (pdf) that daily megadoses of the antioxidant beta-carotene increased the risk of lung cancer in male smokers by 18 percent and a 1996 trial was stopped early after researchers discovered that high-dose beta-carotene and retinol, another form of vitamin A, increased lung cancer risk by 28 percent in smokers and workers exposed to asbestos

IBS treatment includes medications, dietary changes, and lifestyle changes

This could explain the effect of food intake [28,29,30] and exercise [31,32,33,34,35,36,37] on endometriosis and of food supplements such as berberine [38,39], NAC [40], zinc [36,37] and gluten-free diet [41]

BMJ case reports