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While there's no official upper limit, doses up to 2,000 mcg can be safely used to treat B12 deficiency under medical supervision

Harvey CJ, Thimmulappa RK, Sethi S, Kong X, Yarmus L, Brown RH, et al

Growth Hormone Ipamorelin vs GHRP-6 Why Selectivity Matters Ipamorelin vs GHRP-6 compared: selective versus non-selective GH secretagogue signaling, hormonal confounders, and appetite effects