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Abbreviations SAM: S -Adenosylmethionine MLI: Mean liner intercept MAN: Mean alveolar number AECA: Anti-endothelial cell antibodies MDA: Malondialdehyde GSH: Glutathione SOD: Superoxide dismutase GSH-Px: Glutathione peroxidase BALF: Bronchoalveolar lavage fluid AI: Apoptosis index TNF-: Tumour necrosis factor- MMP-9: Matrix metalloproteinase-9 IL-8: Interleukin-8 COPD: Chronic obstructive pulmonary disease SLE: Systemic lupus erythematosus HUVECs: Human umbilical vein endothelial cells SD: Sprague Dawley HE: Haematoxylineosin TUNEL: Terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling References Wellmerling JH, Chang S-W, Kim E, Osman WH, Boyaka PN, Borchers MT, et al