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however, no effective therapies exist for secondary brain injury after ICH (SBI-ICH) (180)

In a rat model of Parkinsons disease (PD) induced by 6-hydroxydopamine (6-OHDA), the systemic administration of the antibody significantly mitigated the degeneration of dopaminergic neurons through the suppression of neuroinflammation, the reduction of ROS generation, and the preservation of BBB integrity [356]

[PubMed: 12167864] 173

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