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Y., Qi, Y., Liao, P., Darakhshan, S., Farzaei, M

The efficacy and safety of sodium-glucose cotransporter 2 inhibitors in patients aged over 80 years with heart failure

Retatrutide adopts a single continuous helix that penetrates the core of the receptor transmembrane domain (TMD) via its N-terminal segment (residues 113), while its C-terminal segment (residues 1430) interacts with the N-terminal -helix of the ECD, the extracellular tip of TM1 and ECL1 (Fig