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Improving blood supply is therefore a rational lever and, notably, it partially overlaps with how minoxidil is thought to help

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16 It is widely expressed in metabolically active tissues, including the liver, heart, skeletal muscle, and adipose tissue, 2325 and is involved in diverse cellular processes such as metabolic homeostasis, antioxidant defense, autophagy, inflammation, and energy balance

In laboratory settings, MOTS-C is commonly explored in research involving stress-induced nuclear translocation, antioxidant response element (ARE) gene expression, and cellular adaptation pathways