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Experimental Physiology

It is for use in cattle, sheep, and swine to provide treatment of Vitamin B deficiencies and to provide a supplemental nutritional source of these vitamins

Another study in the Journal of the American Medical Association notes that among those with diabetic nephropathy (loss of kidney function due to diabetes), combining vitamin B6 (25 mg) and folic acid (2.5 mg) (B-complex vitamin) with 1,000 mcg of oral B12 per day for six years increases the risk of cardiovascular events, including heart attack and stroke

Certain groups of people are more vulnerable to vitamin B deficiency and may benefit from regular supplementation