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Tyrosinase is the enzyme responsible for the formation of melanin in the skin, enclosing two copper atoms surrounded by protein histidine units in the active centre [86]

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In rodents where both CART mRNA transcripts yield proCART proteins the nomenclature of the processed peptide reflects the amino acid numbering of the longer 102 amino acid pro-protein and are identified as CART 55-102 and CART 62-102

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