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Estrogens Impact on Metabolic Processes: Estrogen interacts with specific receptors located in various tissues, including fat cells (adipose tissue), muscle tissue, and the liver, influencing key metabolic processes: Fat Storage and Burning: Estrogen helps store fat in hips and thighs, which is healthier than storing fat around organs

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However, it's important to point out that in the Surmount-4 study, patients were given 2.5 mg of Zepbound and kept upping the dosage up to their maximum tolerated levels of 10mg or 15mg once weekly