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This modification supports extended stability and enables detailed investigation in controlled research environments

As such, effective management of obesity requires a personalized, multidisciplinary approach combining behavioral and dietary interventions, pharmacological therapies, physical activity, and surgery

This complexity suggests that interventions targeting a single mechanism may be insufficient to comprehensively address the disease, thereby building a strong rationale for exploring combined approaches

This small-scale double-blind, randomized clinical trial involved 23 non-surgically treated hospitalized patients, selected to represent the common adult population requiring enteral nutrition in general practice