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Semaglutide, a GLP-1 receptor agonist, works on the same brain regions affected by hormonal shifts, making it a potential option for women navigating midlife weight challenges

By activating GLP-1 receptors in the gut, these medications may help support the intestinal barrier function that is compromised in Hashimoto's patients

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One participant was withdrawn owing to a non-serious adverse event of drug hypersensitivity after IcoSema administration, two participants withdrew consent during the study, and one participant was withdrawn upon decision by the sponsor