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There is a well-established association between bariatric surgery and an increased postoperative risk of suicide, possibly related to unrealistic or thwarted expectations for weight loss, potentiation of the effects of alcohol from alterations in alcohol processing and absorption in the gut, and interference with anti-depressant effect due to pharmacokinetic changes (malabsorption and altered volume of distribution) [185, 186]

( E and F ) Body weight gain in WT ( E ) and Bbs5 / ( F ) mice at 24 and 36 hours after leptin injections

Very high-fat meals linger and amplify nausea