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When used concurrently with insulin or insulin secretagogues such as sulfonylureas or meglitinides, the risk of hypoglycemia may be increased, particularly during the initiation of therapy or following dose escalations

In short: healthy weight loss requires sufficient calories, adequate protein, and mechanical stimulus

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In addition, new evidence from the American Journal of Gastroenterology found no evidence that GLP-1 RAs delay gastric emptying [9]