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The overall incidence of adverse events for the 8-trial, short-term, placebo-controlled pool in adult patients treated with dapagliflozin 10 mg and metformin HCl was 60.3% compared to 58.2% for the placebo and metformin HCl group

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To mimic the postprandial glucose dynamics and high insulin secretion characteristic of PBH, the effect of serotonin on glucose metabolism in response to an insulin-augmented mixed meal tolerance test was assessed