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Frequency varies by patient and goal

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Myocardial ischemia and reperfusion are accompanied by excessive production of reactive oxygen species (ROS), which contribute to ventricular dysfunction, arrhythmogenesis, and cardiomyocyte death

The peptide's antioxidant mechanism operates through activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, a master regulator of cellular antioxidant responses