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Of particular note are the weaker interactions between ICL2 with the N and hns1/S1 region of G s and between H8 and G , in addition to differences in interactions between ICL3/TM6 with the G s 5 helix within the exendin-P5 and oxyntomodulin-bound complexes, compared to GLP-1

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These measurements were merged into several scoring modelsperformance-only, performance-to-weight, cost-weighted value, and balanced value

DPP-4 also cleaves cytokines and chemokines, contributing to inflammation [11]