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Preclinical research has demonstrated these mechanisms extensively, though human clinical trials specific to IGF-1 LR3 are still limited

Researchers working with sensitive skin models should begin with once-daily application and monitor for local reactions before increasing frequency

Wegovy generally provides greater weight loss and may be suitable for those seeking aggressive results Contrave offers an oral alternative for patients who cannot tolerate injections or GLP-1 agonists Ultimately, the best medication depends on your health profile, weight loss goals, lifestyle, and side effect tolerance

Data are presented as the mean SD