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A clinical trial, which enrolled 1,961 adults with a BMI of 30 or greater, or a BMI of at least 27 and at least one weight-related medical problem, found that 86.4% of patients lost more than five percent of their body weight over the course of 68 months when taking a weekly dose of semaglutide

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GLP-1 also helps reduce appetite and food intake, leading to weight loss

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