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Clin Cancer Res 9(12):46274635 Aleshin S, Grabeklis S, Hanck T, Sergeeva M, Reiser G (2009) Peroxisome proliferator-activated receptor (PPAR)-gamma positively controls and PPARalpha negatively controls cyclooxygenase-2 expression in rat brain astrocytes through a convergence on PPARbeta/delta via mutual control of PPAR expression levels

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Ethics declarations Conflict of Interest Fangfang Liu and Nikolaus G

It has been shown that L-glutamine stimulates GLP-1 secretion by activating Gs through Gs-coupled receptors like taste receptor type 1 member 3 (TAS1R3) in intestinal L-cells 28