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These results are consistent with a recent meta-analysis showing that weekly semaglutide injections induce sustained weight loss and improve cardiometabolic risk factors in overweight or obese individuals without diabetes 33

Huadong Pharmaceutical has appealed this ruling but on 31 December 2025, the Supreme Peoples Court in China made a positive decision concerning the intellectual property rights relating to the semaglutide compound patent, and upheld the Beijing IP Court ruling, recognizing the validity of the semaglutide compound patent, until 20 March 2026

When you first open a vial, write the date on the label with a permanent marker

But dehydration amplifies nearly every semaglutide side effect