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The anti-inflammatory gene regulation adds another dimension

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Dietary cuprizone-induced demyelination In this model, mice are fed with the copper chelator cuprizone, leading to oligodendrocyte death and subsequent demyelination followed by spontaneous remyelination, which is initiated during the late demyelination phase and continues robustly over the subsequent 36 weeks after withdrawal of cuprizone

But while the results are impressive, researchers caution that most trials were funded by drugmakers, long term safety data are still limited, and side effects such as nausea are common