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Even one session per week is better than none, but 2-3 provides a good balance for progress and recovery for most beginners

This insulin-independent mechanism provides glucose lowering that is less dependent on beta-cell function, though the glycaemic effect diminishes with declining renal function

Option 3: wait for orforglipron If oral convenience is the primary concern and the timeline works, orforglipron may become available through FDA approval sometime this year