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elegans has been shown to upregulate gcs-1 expression in the intestinal cells via PMK-1-mediated phosphorylation of SKN-1, which leads to the accumulation of SKN-1 into the nuclei [70]
Funding The Project for Enhancing Young and Middle-aged Teachers Research Basis Ability in Colleges of Guangxi (Grant No.2023KY0576)
Gastrointestinal events were the most common adverse effects and were generally consistent with other incretin-based therapies
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