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Semaglutide Semaglutide is a GLP-1 receptor agonist (glucagon-like peptide-1) that mimics the hormone GLP-1, which helps regulate blood sugar and appetite

The PA criteria for Wegovy and Zepbound are similar but not always identical UHC may have different step therapy requirements or formulary placement for each

* The reason -yfgn and -aglr appear at the end of these drug names is to show that the drugs are distinct from each other and from similar medications that may be created in the future

It was developed and FDA-approved in the 1990s (as Geref) to evaluate pituitary function in children with growth hormone deficiency, and it stayed on the market for years before the manufacturer withdrew it in 2009 for commercial reasons, not safety ones