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Subsequent manual adjustments, including fitting the backbone and side chains of the ATD-LBD and LBD-TM3 linkers into the density, as well as deleting unresolved side chains and making subtle local adjustments to minimize clashes, were performed in Coot
From the perspective of signaling pathway regulation, DHRS7 may exert diverse effects by modulating key signaling pathways, such as EGF/EGFR, TGF-, IL-4, PI3K/AKT, and MAPK
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