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In 2009, another GLP-1 agonist, liraglutide, reached the market, followed by the establishment of more GLP-1 agonists in diabetes management [7]
Its important to note that side effects may vary from person to person, but common ones include nausea, constipation and headaches
Contrave produced greater improvements in various cardiometabolic risk markers, participant-reported weight-related quality of life, and eating control
Subsequently, GLP-1s gained FDA approval for weight loss in 2014 (liraglutide: Saxenda/Victoza), 2021 (semaglutide: Wegovy/Ozempic/Rybelsus), and 2023 (tirzepatide: Zepbound/Mounjaro)
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