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Further enhancement of the reducing condition might be an alternative approach for the selective toxicity to NRF2-addicted cancer cells by provoking the reductive stress

Other Mechanisms One study found that a lutein and zeaxanthin supplement decreased the levels of N-retinylidene-N-retinylethanolamine (A2E) and iso-A2E, which is the content of lipofuscin in the RPE of Abca4 (/) / Bco2 (/) double-knockout mice [56]

Various antioxidant enzymes and small molecular free radical scavengers, maintain the delicate balance between oxidants and reductants (antioxidants), crucial to cellular function and fertility

The classical kinetic parameters, Vmax, kcat, and Km, cannot be directly applied to the observed data as catalases do not follow Michaelis-Menten kinetics except at very low substrate concentrations