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doi: 10.1038/gt.2012.81 183 TraisterRSFabreSWangZXiaoXHirschR

In this pilot study, 17 of 34 patients were assigned to the coffee enema plus polyethylene glycol (PEG) 2 L ingestion group, whereas the 17 remaining control patients received 2 L of PEG only

Loke MF, Chua EG, Gan HM, Thulasi K, Wanyiri JW, Thevambiga I, Goh KL, Wong WF, Vadivelu J

As illustrated in Figure 2, these kinases phosphorylate the plasma membrane transporters, shifting them into a state that halts inward reuptake and initiates reverse transport (efflux) mode (Underhill et al., 2020)