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Brain GSH concentrations in all brain regions in the control group were unchanged from baseline to the end of the study (Month 3)

Exhaled CO levels will be measured, and the FTND questionnaire will be administered to assess baseline nicotine dependence

In this study, an increase in total glutathione level in the magnesium treated animals was observed which suggests a potentiation of glutathione production (Table 2)

According to the voltage-driven promotion mechanism of NPT4L and its location on the proximal membrane of the proximal tubule, deeming NPT4 is the main channel for excretion of drugs and UA (Jutabha et al., 2010)