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Reported effects include: Local discomfort at the injection site

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Injury and inflammation to the pigmented layer of the retina (retinal pigment epithelium or RPE) as well as the choroid cause an altered and abnormal diffusion of nutrients to the retina and RPE, possibly precipitating further RPE and retinal damage (Zarbin 2004)

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The relative uptake of each form is likely to influence development investments, branding strategy and ultimately patient adherence

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